134: The Science of Gene Editing & Treating Blindness
For the first time ever we’ve used CRISPR to edit someone’s genes INSIDE THEIR BODY! So far we’ve been able to reverse some effects of rare genetic eye disease that results in blindness, and this is only the beginning!
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References & Further Reading
https://medlineplus.gov/genetics/condition/leber-congenital-amaurosis/ https://rarediseases.info.nih.gov/diseases/634/leber-congenital-amaurosis https://luxturna.com
Gene Therapy https://www.nature.com/articles/d41586-018-06195-6 https://www.nature.com/articles/s41587-020-0493-4 https://www.nature.com/articles/s41573-019-0012-9
The EDIT-101 Trial https://clinicaltrials.gov/ct2/show/study/NCT03872479 https://www.nature.com/articles/s41591-018-0327-9 https://text.npr.org/2021/09/29/1040879179/vision-loss-crispr-treatment https://www.nature.com/articles/d41586-020-00655-8https://www.nature.com/articles/d41586-020-00655-8 https://jamanetwork.com/journals/jama/fullarticle/2764428https://jamanetwork.com/journals/jama/fullarticle/2764428
You can WATCH the podcast over on our YouTube channel:
http://youtube.com/SciGuys
Help keep the show running by supporting us on Patreon!
http://patreon.com/sciguys
If you'd like to see more of us, follow our socials!
http://facebook.com/SciGuysPod
http://twitter.com/SciGuysPod
http://instagram.com/SciGuysPod
Follow the SCI GUYS
@notcorry / @jampkin / @lukecutforth
References & Further Reading
https://medlineplus.gov/genetics/condition/leber-congenital-amaurosis/ https://rarediseases.info.nih.gov/diseases/634/leber-congenital-amaurosis https://luxturna.com
Gene Therapy https://www.nature.com/articles/d41586-018-06195-6 https://www.nature.com/articles/s41587-020-0493-4 https://www.nature.com/articles/s41573-019-0012-9
The EDIT-101 Trial https://clinicaltrials.gov/ct2/show/study/NCT03872479 https://www.nature.com/articles/s41591-018-0327-9 https://text.npr.org/2021/09/29/1040879179/vision-loss-crispr-treatment https://www.nature.com/articles/d41586-020-00655-8https://www.nature.com/articles/d41586-020-00655-8 https://jamanetwork.com/journals/jama/fullarticle/2764428https://jamanetwork.com/journals/jama/fullarticle/2764428