Up First from NPR

Middle East Tensions, South Carolina Primary, Ohio Toxic Train Derailment

President Biden sanctions Israelis for violence in the West Bank. What can turnout in today's South Carolina Democratic primary tell us about the general election in November? One year after a train carrying toxic chemicals derailed in East Palestine Ohio, some residents are still putting their lives back together. Learn more about sponsor message choices: <a href="https://podcastchoices.com/adchoices">podcastchoices.com/adchoices</a> <a href="https://www.npr.org/about-npr/179878450/privacy-policy">NPR Privacy Policy</a>

NPR's Up First is the news you need to start your day. The three biggest stories of the day, with reporting and analysis from NPR News — in 10 minutes. Available weekdays at 6:30 a.m. ET, with hosts Leila Fadel, Steve Inskeep, Michel Martin and A Martinez. Also available on Saturdays at 9 a.m. ET, with Ayesha Rascoe and Scott Simon. On Sundays, hear a longer exploration behind the headlines with Ayesha Rascoe on "The Sunday Story," available by 8 a.m. ET. Subscribe and listen, then support your local NPR station at donate.npr.org. Support NPR's reporting by subscribing to Up First+ and unlock sponsor-free listening. Learn more at plus.npr.org/upfirst